Epithelial organization in development and disease
- Andrés-San Román, J.A., Gordillo-Vázquez, C., Franco-Barranco, D., Morato, L., Tagua, A., Vicente-Munuera, P., Palacios, A.M., Gavilán, M.P., Annese, V., Gómez-Gálvez, P. #, Arganda-Carreras, I. # and Escudero, L.M. # (2023). CartoCell, a high-throughput pipeline for accurate 3D image analysis, unveils cell morphology patterns in epithelial cysts. bioRxiv: 2023.01.05.522724. (# Corresponding authors).
- Gómez-Gálvez, P., Vicente-Munuera, P., Anbari. S., Tagua, A., Gordillo-Vazquez, C.M., Palacios, Franco-Barranco, D., A.M., Velasco, A., Capitan-Agudo, C., Grima, C., Annese, V., Arganda-Carreras, I., Robles, R., Márquez, A., Buceta, J. # and Escudero, L.M. # (2022). A quantitative biophysical principle to explain the 3D cellular connectivity in curved epithelia. Cell Systems, 13 (8). (# Corresponding authors).
- Gómez-Gálvez, P., Vicente-Munuera, P., Anbari S., Buceta, J.#, Escudero, L.M.# (2020). The complex three-dimensional organization of epithelial tissues. Development. Jan 6;148(1). (# Corresponding authors). LINK
- Vicente-Munuera, P., Gómez-Gálvez, P., Tetley, R. J., Forja, C., Tagua, A., Letrán, M., Tozluoglu, M., Mao, Y. #, & Escudero, L. M. # (2020). EpiGraph: an open-source platform to quantify epithelial organization. Bioinformatics, 36(4), 1314–1316. LINK
- Gómez-Gálvez, P., Vicente-Munuera, P., Tagua, A., Forja, C., Castro, A.M., Letrán, M., Valencia-Expósito, A., Grima, C., Bermúdez-Gallardo, M., Serrano-Pérez-Higueras, O., Cavodeassi, F., Sotillos, S., Martín-Bermudo, M.D., Márquez, A., Buceta, J.# and Escudero, L.M.# (2018). Scutoids are a geometrical solution to three-dimensional packing of epithelia. Nature Communications, 9:2960 (# Corresponding authors) LINK
# Blanchard, G. A 3D cell shape that enables tube formation. Nature. 2018 Sep; 561(7722):182-183.
- Vicente-Munuera, P., Gómez-Gálvez, P., Tagua, A., Letrán, M., Mao, Y., Escudero, L.M. (2017). EpiGraph: an open-source platform to quantify epithelial organization. BioRxiv Doi.org/10.1101/217521 LINK
- Sánchez-Gutiérrez, D., Tozluoglu, M., Barry, J.D., Pascual, A., Mao, Y., Escudero, L.M. (2016). Fundamental physical cellular constraints drive self-organization of tissues. EMBO Journal. 35(1):77-88.
- Sánchez-Gutiérrez, D., Sáez, A., Pascual, A., Escudero, L.M. (2013). Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution. PLoS ONE 8(11). LINK
- Escudero, L.M.#, Costa, L. da F., Kicheva, A., Briscoe, J., Freeman, M. and Babu, M. M.# (2011). Epithelial organisation revealed by a network of cellular contacts. Nature Communications 2:526. (# Corresponding authors).
- Vicente-Munuera, P., Gómez-Gálvez, P., Tagua, A., Letrán, M., Mao, Y., Escudero, L.M. (2017). EpiGraph: an open-source platform to quantify epithelial organization. BioRxiv Doi.org/10.1101/217521 LINK
- Sánchez-Gutiérrez, D., Tozluoglu, M., Barry, J.D., Pascual, A., Mao, Y., Escudero, L.M. (2016). Fundamental physical cellular constraints drive self-organization of tissues. EMBO Journal. 35(1):77-88.
- Sánchez-Gutiérrez, D., Sáez, A., Pascual, A., Escudero, L.M. (2013). Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution. PLoS ONE 8(11). LINK
- Escudero, L.M.#, Costa, L. da F., Kicheva, A., Briscoe, J., Freeman, M. and Babu, M. M.# (2011). Epithelial organisation revealed by a network of cellular contacts. Nature Communications 2:526. (# Corresponding authors).
Mathematical analysis in Biomedicine
- Vicente-Munuera, P., Burgos-Panadero, R., Noguera, I., Navarro, S., Noguera, R. #, Escudero, L.M. # (2020). The topology of Vitronectin: a complementary feature for neuroblastoma risk classification based on computer-aided detection. International Journal of Cancer, 146, 553–565. (# Corresponding authors).
- Vicente-Munuera, P., Burgos-Panadero, R., Noguera, I., Navarro, S., Noguera, R. #, Escudero, L.M. # (2020). The topology of Vitronectin: a complementary feature for neuroblastoma risk classification based on computer-aided detection. International Journal of Cancer, 146, 553–565. (# Corresponding authors).
- Piñol-Jurado, P., Suárez-Calvet, X., Fernández-Simón, E., Gallardo, E., de la Oliva, N., Martínez-Muriana, A., Gómez-Gálvez, P., Escudero, L.M., Pérez-Peiró, M., Wollin, L., de Luna, N., Navarro, X., Illa, I., Díaz-Manera, J. (2018). Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy. Cell Death Dis. Jul 10;9(7):776.
- Sánchez-Gutiérrez, D., Sáez, A., Gómez-Gálvez, P., Paradas, C., Escudero, L.M. (2017). Rules of tissue packing involving different cell types: human muscle organization. Sci. Rep. 7, 40444. LINK
- Emmanuele, V., Kubota, A., Garcia-Diaz, B., Garone, C., Akman, H.O., Sanchez-Gutierrez, D., Escudero, L.M., Kariya, S., Homma, S., Tanji, K., Quinzii, C.M., Hirano, M. (2015). Fhl1 W122S causes loss of protein function and late-onset mild myopathy. Hum Mol Genet. 1;24(3):714-26.
- Tadeo, I., Berbegall, A.P., Escudero, L.M., Álvaro, T., Noguera, N. (2014). Biotensegrity of the extracellular matrix: physiology, dynamic mechanical balance and implications in oncology and mechanotherapy. Frontiers in Oncology. 4:39.
- Álvarez-Quilón, A., Serrano-Benítez, A., Lieberman, J. A., Quintero, C., Sánchez-Gutiérrez, D., Escudero, L.M., Cortés-Ledesma, F. (2014). ATM specifically mediates repair of double-strand breaks with blocked DNA ends. Nature Communications. 5:3347. LINK
- Sáez, A., Acha, B., Montero-Sánchez, A., Rivas, E., Acha, B., Escudero, L.M.#, Serrano, C.# (2013). A neuromuscular disease classification system. Journal of Biomedical Optics. 18(6):66017. (# Corresponding authors).
- Sáez, A., Rivas, E., Montero-Sánchez, A., Paradas, C., Acha, B., Pascual, A., Serrano, C., Escudero, L.M. (2013). Quantifiable diagnosis of muscular dystrophies and neurogenic atrophies through network analysis. BMC Medicine 11:77. LINK
- Csikász-Nagy, A., Escudero, L. M., Guillaud, M., Sedwards, S., Baum, B., Cavaliere, M. (2013). Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis. Seminars in Cancer Biology. 23:4, 293-298. LINK
- Sánchez-Gutiérrez, D., Sáez, A., Gómez-Gálvez, P., Paradas, C., Escudero, L.M. (2017). Rules of tissue packing involving different cell types: human muscle organization. Sci. Rep. 7, 40444. LINK
- Csikász-Nagy, A., Escudero, L. M., Guillaud, M., Sedwards, S., Baum, B., Cavaliere, M. (2013). Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis. Seminars in Cancer Biology. 23:4, 293-298. LINK
